Pediatric Hematology
- About Us
- Our Care
- Your Visit
Comprehensive Blood Disorders Care for Kids
91´óÉñ Children’s hematologists (blood disorder experts) are recognized for expertise in treating the full range of cancerous and noncancerous blood disorders in children and teens. We provide complete care for common and rare conditions, from anemia, iron deficiency, and hemophilia to bone marrow failure syndromes, blood cancers, and sickle cell disease.
We’re part of a nationally rankedÌýcancer and blood disorders center of excellence.ÌýHere, many pediatric experts work as one team across multiple locations and specialties in Delaware and Florida. We offer innovative treatments like stem cell transplantation, gene therapies, and advanced infusion services at convenient, kid-friendly locations.
Our pediatric hematologists partner with scientists and researchers to improve care for kids. We’re a sickle cell research center offering the most up-to-date treatment. We participate in studies that advance care for children with immune thrombocytopenia. We’re a designated, accredited pediatric hemophilia treatment center, offering the full range of services. And we offer many clinical trials and treatments you can’t get everywhere.Ìý
Beyond our doctors, you'll have a dedicated team of nurses, social workers, psychologists, nutritionists, and Child Life specialists who understand what your child is going through. They're here to answer questions, provide support, and help your whole family navigate this journey together.
Nationally Recognized Cancer and Blood Disorders Center
The 91´óÉñ Center for Cancer and Blood Disorders (NCCBD) is a place where children and young adults get the highest level of care in a comforting, family-centered environment. We’re one of the largest programs of its kind. With three regional locations throughout the Delaware Valley and Florida, we offer access to the most promising new treatments, often years before they're available elsewhere.Ìý
See how our collaborative approach, groundbreaking research, focused support and state-of-the-art facilities give kids with cancer the best chance for a long, healthy live.
Anemia is when the number of red blood cells in the body gets too low. Learn more about anemia from the experts at 91´óÉñ KidsHealth®.
Sickle cell disease is a health problem that makes a person's red blood cells become C-shaped or curved like a sickle instead of round.Ìý
Nationally Recognized Blood Disorders Care for Kids
We’re a multistate network that brings together the highest level of experience in pediatric hematology. This means your child benefits from the combined expertise of specialists across our system, partnering to create a personalized treatment plan just for them.
3
Regional blood disorder center locations, in Delaware and Florida
300+
Children with sickle cell disease we care for each year, systemwide
30+
Specialties we work with daily
Kids with sickle cell get complete care, including innovative therapies to reduce complications and improve quality of life.
As aÌýdesignated Hemophilia Foundation treatment center for children with bleeding and clotting disorders,Ìýwe offer specialized care and supportÌýfor managing daily activities.
OurÌýprogram is accreditedÌýby the Foundation for Accreditation of Cellular Therapies (FACT).
You haveÌýaccess to treatments before they're widely available, as we’re one of three kids-onlyÌýNational Cancer Institute’s Community Oncology Research Programs (NCORP) in the country.
Our Northeast Florida Chief
D. Anderson Collier is a pediatric hematologist/oncologist at 91´óÉñ Children's Health, Jacksonville. Dr. Collier has been an active researcher and was the principal investigator for Children's Oncology Group (COG) work at the University of Mississippi Medical Center, as well as director of pediatric oncology research. He has published book chapters and peer-reviewed medical journal articles, is a reviewer for theÌýJournal of Pediatric Hematology Oncology,Ìýand an academic editor for the journalÌýMedicine. Watch the video and meet him.Ìý
Meet Pediatric Hematology Team
Your child's success is our mission. Every member of our stem cell transplant and cellular therapy team is committed to providing not just advanced treatment, but truly life-changing care for kids.Ìý
-
Kelly Anne Ryan, MD
Cardiac Anesthesia Clinical Assistant Professor of Anesthesiology and Pediatrics at Sidney Kimmel Medical College, Thomas Jefferson UniversityPrimary Office
Wilmington, DE -
Ellen A. Spurrier, MD
Cardiac Anesthesia Chief, Division of Cardiac Anesthesiology Clinical Associate Professor of Anesthesiology and Pediatrics at Sidney Kimmel Medical College, Thomas Jefferson UniversityPrimary Office
Wilmington, DE
Nationally Recognized Blood Disorders Care for Kids
We’re a multistate network that brings together the highest level of experience in pediatric hematology. This means your child benefits from the combined expertise of specialists across our system, partnering to create a personalized treatment plan just for them.
3
Regional blood disorder center locations, in Delaware and Florida
300+
Children with sickle cell disease we care for each year, systemwide
30+
Specialties we work with daily
We're ranked among theÌýtop programs in the country and have received the largest National Institutes of Health grant for sickle cell disease research, leading to breakthrough treatments.
Kids with sickle cell get complete care to reduceÌýcomplications and improve quality of life.
As Delaware's only federally funded center for children with bleeding and clotting disorders, we offerÌýcare that includes prevention, surgical planning, and supportÌýfor managing daily activities.
Your child may haveÌýaccess to treatments before they're widely available, as we’re one of three kids-onlyÌýNational Cancer Institute’s Community Oncology Research Programs (NCORP) in the country.
Our Delaware Valley Chief
Dr. Corinna L. Schultz is a pediatric hematologist/oncologist at 91´óÉñ Children’s Hospital, Delaware and an assistant professor at Sidney Kimmel Medical College. She's an invited lecturer, presenter, published medical journal author, active researcher, and member of multiple medical societies, serving on a national committee of the Children's Oncology Group (COG). Watch the video and meet her.Ìý
Meet Our Pediatric Hematology Team
Your child's success is our mission. Every member of our blood disorders team is committed to providing not just advanced treatment, but truly life-changing care for kids.Ìý
Nationally Recognized Blood Disorders Care for Kids
We’re a multistate network that brings together the highest level of experience in pediatric hematology. This means your child benefits from the combined expertise of specialists across our system, partnering to create a personalized treatment plan just for them.
3
Regional blood disorder center locations, in Delaware and Florida
300+
Children with sickle cell disease we care for each year, systemwide
30+
Specialties we work with daily
In Delaware, we’re ranked among theÌýtop programs in the country and have received the largest National Institutes of Health grant for sickle cell disease research, leading to breakthrough treatments.
Kids with sickle cell get complete careÌýto reduce complications and improve quality of life.
We’reÌýrecognized for bleeding and clotting disorders care, including prevention, surgical planning, and supportÌýfor managing daily activities.
Your child may haveÌýaccess to treatments before they're widely available, as we’re one of three kids-onlyÌýNational Cancer Institute’s Community Oncology Research Programs (NCORP) in the country.
Leadership Spotlight: Delaware Valley Cancer Center Chief
Dr. Corinna L. Schultz is a pediatric hematologist/oncologist at 91´óÉñ Children’s Hospital, Delaware and an assistant professor at Sidney Kimmel Medical College. She's an invited lecturer, presenter, published medical journal author, active researcher, and member of multiple medical societies, serving on a national committee of the Children's Oncology Group (COG). Watch the video and meet her.Ìý
Meet Our Pediatric Hematology Team
Your child's success is our mission. Every member of our blood disorders team is committed to providing not just advanced treatment, but truly life-changing care for kids.Ìý
-
Kelly Anne Ryan, MD
Cardiac Anesthesia Clinical Assistant Professor of Anesthesiology and Pediatrics at Sidney Kimmel Medical College, Thomas Jefferson UniversityPrimary Office
Wilmington, DE -
Ellen A. Spurrier, MD
Cardiac Anesthesia Chief, Division of Cardiac Anesthesiology Clinical Associate Professor of Anesthesiology and Pediatrics at Sidney Kimmel Medical College, Thomas Jefferson UniversityPrimary Office
Wilmington, DE
Specialized CareÌýfor Kids With Blood Disorders
At 91´óÉñ Children's, we guide you forward with confidence. Our team doesn’t just treat conditions. We care for the whole child, bringing together advanced medical expertise with the genuine understanding that makes a real difference in your family's journey.
We offer services that support your whole family, including genetic counseling, pain management specialists, transition programs for teens moving to adult care, and educational resources.
Our Programs & ServicesÌýÌý
Bleeding & Clotting Disorders ProgramÌý
Complete care for hemophilia, von Willebrand disease, and other bleeding and clotting disorders. Our team provides specialized treatment plans, ranging from preventive care to surgical planning, with dedicated care for adolescents and young adults.
Bone Marrow Failure Program
Expert diagnosis and treatment for rare bone marrow disorders, offering advanced cellular therapies and transplant options. Our program brings together specialists in hematology, genetics, and supportive care to create personalized treatment plans for complex conditions.
Sickle Cell Disease Program
Research-driven care for children with sickle cell disease and other hemoglobinopathies. We offer innovative treatments, stroke prevention, and supportive care including pain management, transfusion services, and dedicated support to help children thrive from diagnosis through adolescence.
Leukemia & Lymphoma Cancer Program
Advanced care for leukemia, lymphoma, and other blood cancers, offering the latest cellular therapies and some of the nation's highest clinical trial enrollment rates. Our team specializes in complex cases and rare blood cancers.
Advanced Treatment Options & Support

Our program brings together experts from multiple specialties to deliver innovative treatments, all in one place. We offer:
- Blood and bone marrow transplants: Our transplant program offers innovative treatments for blood disorders including sickle cell disease, thalassemia, and bone marrow failure syndromes.
- Gene therapy: We provide cutting-edge gene therapy options for select blood disorders. We’re at the forefront in the field, offering therapies that target the underlying genetic causes of conditions like sickle cell disease.
- Transfusion and apheresis services: Our specialized infusion centers provide blood transfusions, red blood cell exchange (erythrocytopheresis), and factor replacement therapies. Treatments take place in a child-friendly environment.
- Disease-modifying therapies: We provide the latest treatments to help manage blood disorders effectively, including advanced medications that can change the course of conditions like sickle cell disease and hemophilia.
- Clinical trials and research treatments: Through our active research, we offer access to promising new treatments for sickle cell disease and other blood disorders before they're widely available.
Comprehensive Support Services
Living with a blood disorder affects every part of a child's life. That's why our care extends far beyond medical treatment. Our comprehensive support team surrounds your family with expertise and understanding, including:
- Child Life specialists who help your child understand their condition and cope through play and creative therapies, making medical experiences less scary and more manageable.
- Social workers and counselors who provide emotional support, connect you with community resources, and help navigate school and lifestyle adjustments.
- Pain management specialists who develop personalized plans to prevent and manage pain, particularly for conditions like sickle cell disease.
- Genetic counselors who help families understand inherited blood disorders and guide them through important health decisions.
- Physical therapists who work to maintain strength and mobility, especially important for children with hemophilia or other bleeding disorders.
- Nutrition specialists who ensure your child maintains proper nutrition and iron levels to support their overall health and treatment success.
- School advocacy team who partners with your child's school to make sure they receive proper accommodations and support and help them stay on track academically while managing their condition.
- Transition specialists who help adolescents and their families prepare for the move to adult care for continued success in managing their condition.
Conditions We Treat
We see a wide range of conditions — far too many to list here. The conditions we treat vary depending on the location and providers selected. Don’t see a condition listed? Call us.
Related Specialties & Programs

Care for International Families
Find out how the 91´óÉñ International Medicine Program helps children — no matter where they live — have a healthier and happier future. We’ve cared for hundreds of patients from around the world, in nearly every pediatric specialty. You can count on our expert care and reliable interpreter services. We can assist with housing, transportation and other services too.
Care That Goes Beyond Medicine
When your family comes to 91´óÉñ, you’re well cared for. We want you to understand your child’s condition and how to help them stay healthy and succeed. We help you find community resources for your family. We also offer many supportive services, like social work, lodging at nearby Ronald McDonald Houses, creative therapies, pet therapy, Child Life programs and much more.


Convenient Follow-Up Appointments by Video
We offer follow-up appointments through scheduled, live video visits. You can avoid waiting rooms and save travel time. Ask your doctor if this is an option for your family.
What to Expect
From your first visit at 91´óÉñ Children's, you'll have an entire team walking beside you. While every child's care plan is different, understanding common treatments can help your family feel more prepared. We're here to guide you through each step, answer your questions, and provide the support you need.
Blood Transfusions
What it Is: A procedure that provides healthy blood cells when your child's body isn't making enough.
How it Works: We carefully match donated blood to your child's blood type and deliver it intravenously (through an IV line) while monitoring closely.
What to Expect: Sessions can last 2-4 hours. Some children need regular transfusions while others may only need them occasionally.
from 91´óÉñ KidsHealth®.
Red Blood Cell Exchange (Erythrocytopheresis)
What it Is: A specialized treatment that removes abnormal red blood cells and replaces them with healthy ones.
How it Works: Using a special machine, we separate and remove affected blood cells while returning healthy cells to the body.
What to Expect:Treatment sessions are typically done in our infusion center and can last several hours.
Stem Cell (Bone Marrow) Transplant
What it Is: A treatment that replaces damaged bone marrow with healthy stem cells to treat certain blood disorders.
Types of transplants:
- Using your child's own cells
- Using cells from a matched donor
- Using donated umbilical cord blood
What to Expect: A treatment that replaces damaged bone marrow with healthy stem cells to treat certain blood disorders.
Find stem cell transplant care at 91´óÉñ.
from 91´óÉñ KidsHealth.
Disease-Modifying Therapies

What it Is: Advanced medications that treat the underlying cause of blood disorders.
How it Works: Different medications work in various ways. Some prevent sickling of red blood cells, others boost blood cell production or modify how the body produces certain proteins.
What to Expect:May be given as regular infusions, daily medications, or periodic treatments depending on the specific therapy.
Iron Chelation Therapy
What it Is: Treatment to remove excess iron from the body that can build up from regular blood transfusions.
How it Works: Medication given either through an infusion or by mouth that binds to excess iron so the body can remove it.
What to Expect: Regular monitoring of iron levels and ongoing adjustments to therapy as needed.
Gene Therapy
What it Is: Cutting-edge treatment that targets the genetic causes of certain blood disorders.
How it Works: Uses modified viruses or other techniques to deliver corrected genes or modify existing ones.
What to Expect: Currently available for select conditions through clinical trials and approved treatments. Requires careful evaluation and monitoring.
from 91´óÉñ KidsHealth.
More About Sickle Cell From 91´óÉñ KidsHealth

The 91´óÉñ KidsHealth Sickle Cell Topic Center offers trusted, easy-to-understand information to help families navigate life with sickle cell disease. Our experts offer:
- Clear explanations about sickle cell disease, trait inheritance, and available treatments in parent-friendly language.
- Strategies for preventing and managing pain crises at home and knowing when to seek emergency care.
- Practical tips for school, sports and staying active while managing the condition.
- Guidance on nutrition, hydration, and maintaining overall wellness.
- Information about developmental milestones and helping your child grow up healthy with sickle cell.
- Resources for talking to extended family members about sickle cell trait and inheritance.
- Age-appropriate articles to help children understand their condition and take an active role in their care.
- Support for parents in managing medications, appointments, and daily care routines.